The association between duration of muscle exercise and psychological symptoms is higher in boys than in girls: A cross-sectional study based on Chinese college students during COVID-19.

Objective: The COVID-19 pandemic has had many negative effects on the physical and mental health of college students. Although many studies have analyzed the association between muscular fitness and psychological symptoms in children and adolescents, research during the COVID-19 pandemic is limited. Our study focused on analyzing the association between duration of muscle exercise and psychological symptoms among Chinese college students during the COVID-19 pandemic. Method: A four-stage stratified whole-group sampling method was used to investigate basic demographic information, duration of muscle exercise and psychological symptoms in 5,559 college students aged 19-22 years in China. Chi-square test (categorical variables) and one-way ANOVA (continuous variables) were used to compare the psychological symptoms of college students with different durations of muscle exercise. Logistic regression analysis was used to analyze the association between duration of muscle exercise and psychological symptoms. Result: The detection rate of psychological symptoms among Chinese college students was 9.0%; the detection rate was 10.7% for boys and 7.6% for girls. The proportions of duration of muscle exercise at <30 min/d, 30-60 min/d, and >60 min/d were 75.0%, 20.4%, and 4.6%, respectively. After adjusting for relevant confounding variables, taking Chinese college students with duration of muscle exercise >60 min/d as the reference group, duration of muscle exercise <30 min/d was positively correlated with the occurrence of psychological symptoms (OR: 4.19, 95%CI: 1.82, 9.61) (P < 0.001). In emotional symptoms (OR: 4.56, 95%CI: 1.99, 10.44), behavioral symptoms (OR: 3.44, 95%CI: 1.79, 6.60), social adaptation difficulties (OR: 3.04, 95%CI: 1.62, 5.68) dimensions, there is also a positive correlation (P < 0.01). Conclusions: The negative association between duration of muscle exercise and psychological symptoms among Chinese college students also suggests that longer duration of muscle exercise among college students is associated with a lower prevalence of psychological symptoms. The association between duration of muscle exercise and psychological symptoms was higher in boys compared to girls.

Follow-Up CT Results of COVID-19 Patients with Initial Negative Chest CT.

PURPOSE: To determine whether new pulmonary lesions will develop in COVID-19 patients with negative initial chest CT findings and to investigate their CT features and outcome during treatment. PATIENTS AND METHODS: Data were collected retrospectively from 29 patients who had tested positive for COVID-19 by reverse-transcription polymerase chain reaction testing but negative by initial chest CT from January 22 to February 17, 2020. Clinical manifestations, laboratory indicators, and follow-up CT data were evaluated. RESULTS: Among 317 confirmed COVID-19 patients, 29 (9.1%) (mean ± SD, 38.5 ± 20.5 years; 12 women) with negative initial chest CT findings were evaluated. New pulmonary lesions developed in 10 (34.5%) patients on follow-up CT. Mean time from onset of new lesions to initial CT was 5.8 ± 3.0 days (range: 2-12 days). New lesions (mean involved lobes and segments: 2.5 ± 1.6 [range: 1-5] and 4.5 ± 4.5 [range: 1-13]) were mainly spherical/patchy ground-glass opacities frequently located in the left lower lobe (9, 90.0%). Among the 10 patients, lesions in 6 (60.0%) indicated progression after occurrence, and those in 10 (100.0%) indicated significant absorption on latest CT. When new lesions developed, 6 (60.0%) patients developed new symptoms or had aggravated symptoms and 3 (30.0%) had decreased lymphocyte count. Patients with worsening symptoms had higher involvement of lung segments (mean: 6.5 ± 5.0, range: 1-13) than asymptomatic patients (mean: 1.5 ± 0.6, range: 1-2) (P = 0.057). CONCLUSION: In COVID-19 patients with negative initial chest CT findings, new pulmonary lesions may develop during treatment. Repeat CT is necessary for monitoring the disease, especially when patients have worsening symptoms or laboratory indicators.

Completed absorption of coronavirus disease 2019 (COVID-19) pneumonia lesions: a preliminary study.

Background: Complete absorption of coronavirus disease 2019 (COVID-19) pneumonia in a short term was not detailedly reported. We aimed to investigate the clinical and imaging characteristics of COVID-19 patients with complete absorption of pulmonary lesions. Methods: Retrospectively collected the clinical and chest CT data of 224 patients with COVID-19 in one regional medical center. Currently, pulmonary lesions in 37 patients were completely absorbed. The clinical manifestations, laboratory examinations, and CT findings of lesions for these patients were summarized. Results: Among the 37 patients (age, 39.0 ± 12.4 [14-63] years, 20 males), disease in 36 (97.3%) was mild and in 1 (2.7%) was from severe to mild. The most common symptoms were cough (24/37, 64.9%) and fever (23/37, 62.2%). Their laboratory indicators at admission were usually normal, while the white blood cell and neutrophil count significantly increased at discharge (p = 0.004, p = 0.006). On initial CT images, all patients had various pulmonary lesions (mean involved lobes: 2.8 ± 1.5, range: 1-5; mean involved segments: 6.6 ± 4.3, range: 1-16), which mainly manifested as multiple patchy and or spherical ground glass opacities (GGOs) (30/37, 81.1%) with fibrous strips (19/30, 63.3%) or consolidation (11/30, 36.7%). After treatment, lesions in most (33/37, 89.2%) patients were continuously absorbed. At discharge, previous lesions were mostly absorbed in 11 patients (11/37, 29.7%), the main residues were GGOs (24/37, 64.9%), followed by fibrous strips (13/37, 35.1%). On the latest CT, all the pulmonary lesions were completely absorbed, the duration of lesions was 31.6 ± 11.4 days (range: 5-50 days). Conclusion: The pulmonary lesions in some mild COVID-19 patients (generally with normal laboratory indicators at admission, GGOs as the main manifestation on initial CT, and representation of continuous absorption after treatment) could be completely absorbed with a mean duration of 31.6 days.